Nebulized surfactant as a treatment choice for otitis media with effusion: an experimental study in the rabbit


KOTEN M., UZUN C., YAGIZ R., KEMAL M., ADALI K., KARASALIHOGLU A., ...More

JOURNAL OF LARYNGOLOGY AND OTOLOGY, vol.115, no.5, pp.363-368, 2001 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 115 Issue: 5
  • Publication Date: 2001
  • Doi Number: 10.1258/0022215011907848
  • Title of Journal : JOURNAL OF LARYNGOLOGY AND OTOLOGY
  • Page Numbers: pp.363-368

Abstract

Exogenous surfactant can improve eustachian tube function in experimentally induced otitis media with effusion (OME). Performing tympanometric recordings, the efficacy of inhaled nebulized surfactant, as compared with inhaled nebulized physiological saline was investigated, for the treatment of OME experimentally induced in the rabbit by intrabullar inoculation of heat-killed Streptococcus pneumoniae. In addition, the histological changes in middle ears after the treatment were investigated in order to establish whether the pathological findings correlated with the results.