Osmangazi Tıp Dergisi, vol.43, no.1, pp.82-85, 2021 (Peer-Reviewed Journal)
Serotonin syndrome is a potentiallyfatalconditioncaused by overstimulation of serotonin receptors in the centraland peripheralnervous system. Serotonin syndrome developsdueto the increasedamount of serotonin duetoincreasedserotoninsynthesisorrelease, decreasedmetabolism, inhibition of reuptakeand / ordirectagonistic to serotonin receptors. Intheliterature, rarecases of serotoninsyndromeduetolinezolid have been reported. Inthisreport, wepresent a case of serotoninsyndromedeveloped in a patientreceivinglinezolid therapy fordiabetic foot infectionandreceivingescitalopramtreatment for major depression.
Keywords: Linezolid, escitalopram, serotonin syndrome