Protective role of heparin in the injury of the liver and kidney on the experimental model of ischemia/reperfusion

Yener, ALİ; CICEK, Mustafa; Genc, Serhat; ÖZKAN, Turgut; DOGAN, Emre; BILGIN, Bulent; AKIN, Tezcan; Erdem, Havva; Ankarali, Handan

doi:10.1186/1749-8090-9-35

Protective role of heparin in the injury of the liver and kidney on the experimental model of ischemia/reperfusion

Atıf İçin Kopyala

Yener A. Ü. , CICEK M. C. , Genc S. B. , ÖZKAN T., DOGAN E., BILGIN B. C. , ...Daha Fazla

JOURNAL OF CARDIOTHORACIC SURGERY, cilt.9, 2014 (SCI İndekslerine Giren Dergi)

Cilt numarası: 9
Basım Tarihi: 2014
Doi Numarası: 10.1186/1749-8090-9-35
Dergi Adı: JOURNAL OF CARDIOTHORACIC SURGERY

Özet

Background: Surgery of thoracoabdominal aortic aneurysms (TAAA) is associated with high incidence of serious complications. Ischemia/reperfusion (I/R) injury may be responsible for these complications. We investigated the effect of degree of anticoagulation on remote organ I/R injuries and whether heparin is protective against I/R injury in addition to its anticoagulant properties.