Protective role of heparin in the injury of the liver and kidney on the experimental model of ischemia/reperfusion

Yener A. Ü. , CICEK M. C. , Genc S. B. , ÖZKAN T., DOGAN E., BILGIN B. C. , ...More

JOURNAL OF CARDIOTHORACIC SURGERY, vol.9, 2014 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9
  • Publication Date: 2014
  • Doi Number: 10.1186/1749-8090-9-35
  • Journal Name: JOURNAL OF CARDIOTHORACIC SURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus

Abstract

Background: Surgery of thoracoabdominal aortic aneurysms (TAAA) is associated with high incidence of serious complications. Ischemia/reperfusion (I/R) injury may be responsible for these complications. We investigated the effect of degree of anticoagulation on remote organ I/R injuries and whether heparin is protective against I/R injury in addition to its anticoagulant properties.