Dietary supplementation of olive leaf extract enhances growth performance, digestive enzyme activity and growth related genes expression in common carp Cyprinus carpio

Zemheri-Navruz F., ACAR Ü., YILMAZ S.

GENERAL AND COMPARATIVE ENDOCRINOLOGY, vol.296, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 296
  • Publication Date: 2020
  • Doi Number: 10.1016/j.ygcen.2020.113541
  • Journal Name: GENERAL AND COMPARATIVE ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Animal Behavior Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), Artic & Antarctic Regions, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: Phytochemical, Gene regulation, Digestive enzyme, Growth performance, Common carp, Olive leaf extract
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

It is not desirable to use synthetic chemicals as growth promoters in aquaculture. Therefore, phytogenic compounds have been extensively studied in fish diets due to their growth promoter effects. Common carp (Cyprinus carpio) is widely distributed around the world and has been reared in Asia for several centuries. This study was conducted to determine the effects of olive leaf extract (OLE) (0, 0.1, 0.25, 0.50 and 1%) on the growth performance, digestive enzyme activity in the intestine and the expression levels of some growth-related genes in the brain. liver, head kidney and mucsle tissue of common carp C. carpio. At the end of the 60-day feeding period, there was a significant increase in growth performance in the OLE0.1 and OLE0.25 groups. Similar trends have been obtained for digestive enzyme activities such as a-amylase, protease and lipase. Morover, the expression of growth hormone (GH) and insulin-like growth factor I (IGF-I) was regulated by OLE supplemented by up to 0.25% in brain, liver, head kidney and muscle tissue. This study confirms that dietary OLE may enhance the growth performance of the common carp by activating the digestive enzyme activity in the intestine and increase the expression of genes (GH and IGF-I) related with growth in brain, liver, head kidneys and muscle tissue of common carp up to use 0.10% in diets.