Curcumin-selenium nanoparticles: A promising approach in disease prevention and treatment

Ghoflchi S., KARAV S., Hosseini H., Sahebkar A.

Journal of Trace Elements in Medicine and Biology, cilt.94, 2026 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 94
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1016/j.jtemb.2026.127824
  • Dergi Adı: Journal of Trace Elements in Medicine and Biology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Anahtar Kelimeler: Antioxidant, Curcumin, Inflammation, Selenium
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Curcumin, the primary active ingredient from turmeric's rhizome, and selenium, a vital human element, have received significant scientific attention in medical research. The combination of curcumin and selenium has been considered an emerging approach to preventing and treating diseases due to their ability to reduce oxidative stress, regulate inflammation, and enhance the immune system. The use of nanotechnology, especially in the form of curcumin-selenium nanoparticles (CurSeNPs), has provided a novel solution to overcome the limitations of the use of curcumin and selenium, such as the low bioavailability of curcumin and the toxicity of selenium at high doses. This review aims to explore the research on the effects of CurSeNPs on various diseases and assess their therapeutic potential. This review aims to evaluate previous studies exploring the effects of Cur–SeNPs on various diseases.