Alpha-synuclein levels in multiple sclerosis patients with restless leg syndrome

ÇAKINA S., YÜCEL S., ÇAĞAN POLAT C., ÖZTÜRK Ş.

CUKUROVA MEDICAL JOURNAL, cilt.45, sa.2, ss.562-567, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.17826/cumj.674564
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.562-567
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Purpose: The restless legs syndrome is more frequent and critical in Multiple Sclerosis patients, and it harms their general well-being and life quality. Alpha-synuclein is a synuclein protein that can have an impact on the pathway of signaling, affecting the Dopamin 2 receptor and its receptor trafficking. Studies have shown that the decrease in dopamine 2 receptor and Restless Legs Syndrome disease are correlated. This study is aimed to ascertain the alpha-synuclein level in multiple sclerosis patients with restless legs syndrome.