Alpha-synuclein levels in multiple sclerosis patients with restless leg syndrome


ÇAKINA S. , YÜCEL S. , ÇAĞAN POLAT C. , ÖZTÜRK Ş.

CUKUROVA MEDICAL JOURNAL, vol.45, no.2, pp.562-567, 2020 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.17826/cumj.674564
  • Title of Journal : CUKUROVA MEDICAL JOURNAL
  • Page Numbers: pp.562-567

Abstract

Purpose: The restless legs syndrome is more frequent and critical in Multiple Sclerosis patients, and it harms their general well-being and life quality. Alpha-synuclein is a synuclein protein that can have an impact on the pathway of signaling, affecting the Dopamin 2 receptor and its receptor trafficking. Studies have shown that the decrease in dopamine 2 receptor and Restless Legs Syndrome disease are correlated. This study is aimed to ascertain the alpha-synuclein level in multiple sclerosis patients with restless legs syndrome.