In Vivo Evaluation of the Genotoxic Effects of Gonadotropins on Rat Reticulocytes

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Duran B., Koc O., OZDEMIRCI S., Topcuoglu A., ÖZDEMİR Ö.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, vol.72, no.2, pp.60-70, 2011 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 72 Issue: 2
• Publication Date: 2011
• Doi Number: 10.1016/j.curtheres.2011.03.003
• Journal Name: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.60-70
• Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

BACKGROUND: Gonadotropins, as ovulation-inducing drugs, have been used widely to treat infertility. An epidemiologic correlation between infertility therapy and ovarian cancer development has been reported. However, the effect of gonadotropins in the formation of reproductive tract cancers is controversial.