Comparison of the Therapeutic Efficacy of Linezolid and Vancomycin and Correlation of Serum and Tissue Malondialdehyde and Myeloperoxidase in an Experimental Mediastinitis Model

Sacar, Suzan; Sacar, MUSTAFA; Aybek, Hulya; Turgut, Huseyin; Onem, Gokhan; Cevahir, Nural; Teke, Zafer; Kaleli, Iknur; GULER, Adem; UCAK, Alper; Baltalarli, Ahmet

doi:10.1016/j.jss.2008.03.040

Comparison of the Therapeutic Efficacy of Linezolid and Vancomycin and Correlation of Serum and Tissue Malondialdehyde and Myeloperoxidase in an Experimental Mediastinitis Model

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Sacar S., Sacar M., Aybek H., Turgut H., Onem G., Cevahir N., ...More

JOURNAL OF SURGICAL RESEARCH, vol.152, no.1, pp.89-95, 2009 (SCI-Expanded)

Publication Type: Article / Article
Volume: 152 Issue: 1
Publication Date: 2009
Doi Number: 10.1016/j.jss.2008.03.040
Journal Name: JOURNAL OF SURGICAL RESEARCH
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.89-95
Çanakkale Onsekiz Mart University Affiliated: No

Abstract

Background. We aimed to investigate the therapeutic efficacy of linezolid in an experimental mediastinitis model and to compare it with vancomycin, which is commonly used. The objective of this study was also to evaluate the role of the immune system in mediastinitis.