Comparison of the Therapeutic Efficacy of Linezolid and Vancomycin and Correlation of Serum and Tissue Malondialdehyde and Myeloperoxidase in an Experimental Mediastinitis Model


Sacar S., Sacar M., Aybek H., Turgut H., Onem G., Cevahir N., ...More

JOURNAL OF SURGICAL RESEARCH, vol.152, no.1, pp.89-95, 2009 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 152 Issue: 1
  • Publication Date: 2009
  • Doi Number: 10.1016/j.jss.2008.03.040
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.89-95

Abstract

Background. We aimed to investigate the therapeutic efficacy of linezolid in an experimental mediastinitis model and to compare it with vancomycin, which is commonly used. The objective of this study was also to evaluate the role of the immune system in mediastinitis.