Efficacy of linezolid in the treatment of mediastinitis due to methicittin-resistant Staphylococcus aureus: an experimental study

Sacar M., Sacar S., Kaleli L., Cevahir N., Teke Z., Kavas S. T., ...Daha Fazla

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, cilt.12, sa.4, ss.396-401, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 4
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.ijid.2007.09.017
  • Dergi Adı: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.396-401
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Hayır

Özet

Introduction: The treatment of postoperative mediastinitis is very important because of its high morbidity, mortality, and increased hospital stay and hospital costs. The aims of our research were to investigate whether linezolid alone can be an effective treatment agent for methicillin-resistant Staphylococcus aureus (MRSA) mediastinitis, and to determine whether linezolid can provide synergistic activity when given in combination with rifampin.