Biosensing strategies for diagnosis of prostate specific antigen

ÖZYURT C., ULUDAĞ İ., Ince B., SEZGİNTÜRK M. K.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, vol.209, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 209
  • Publication Date: 2022
  • Doi Number: 10.1016/j.jpba.2021.114535
  • Journal Name: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Analytical Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chimica, EMBASE, International Pharmaceutical Abstracts, MEDLINE, Veterinary Science Database
  • Keywords: Biosensors, PSA, Cancer marker detection, Prostate specific antigen, SURFACE-PLASMON RESONANCE, FREE ELECTROCHEMICAL IMMUNOSENSOR, CRYSTAL MICROBALANCE SENSORS, HIGHLY SENSITIVE DETECTION, ENERGY-TRANSFER, PHOTOELECTROCHEMICAL IMMUNOSENSOR, ULTRASENSITIVE DETECTION, CANCER BIOMARKERS, QCM SENSOR, IMMUNOASSAY
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Almost from the time of its discovery, the prostate specific antigen (PSA) has been one of the most accurate and most extensively studied indicators of prostate cancer (PC). Because of advancements in biosensing systems and technology, PSA analysis methods have been substantially updated and enhanced as compared to their first instances. With the development of techniques in biosensor technology, the number of PSA biosensors that can be used in the biomedical sector is increasing year by year. Many different recognition elements and transducers have been used in the development of biosensor systems that exhibit high sensitivity, selectivity, and specificity. Here in this review, we provide a current overview of the different approaches to PSA detection. (c) 2021 Published by Elsevier B.V.