Akademik Veri Yönetim Sistemi
Medeniyet Medical Journal, cilt.23, sa.3, ss.81-84, 2008 (Scopus)
Amaç: Tüberküloz plörezi ve parapnömonik efüzyon Türkiye’de en s›k görülen plevral efüzyon nedenleridirler. Bu çal›flman›n amac› enfeksiyöz s›v›lar›n ayr›c› tan›s›nda biyokimyasal karakteristiklerini de¤erlendirmektir.
Materyal ve Metod: Bir üniversite hastanesinde torasentez
yap›lm›fl 62 konjestif kalp yetmezlikli, 44 parapnömonik efüzyonlu ve 26 tüberküloz plörezili hastan›n serum ve plevra s›v›-
s› biyokimyasal özellikleri retrospektif olarak incelendi. ‹statistiksel analiz SPSS program›n›n 10.0 versiyonu kullan›larak
yap›ld›.
Bulgular: Hastalar›n ortalama yafllar› tüberküloz plörezi için
37, parapnömonik efüzyon için 40 ve konjestif kalp yetmezli¤i
için 64 idi. Di¤er gruplarla k›yasland›¤›nda tüberküloz plörezi olgular›nda kilo kayb› anlaml› derecede daha s›kt›. S›v›da
total lökosit say›s› transuda grubunda 556/mm3, tüberküloz
için 11424/mm3, parapnömonik efüzyon için 8260/mm3 idi.
Tüberküloz plörezi ve parapnömonik efüzyon gruplar› aras›nda plevra s›v›s› LDH düzeyi, plevra s›v›s› LDH’inin serum
LDH’ye oran›, plevra s›v›s› total protein ve albümin düzeyi ve
plevra s›v›s› total proteininin serum total proteinine oran› aç›-
s›ndan anlaml› bir farkl›l›k yoktu.
Sonuç: Plevra s›v›s› veya seruma dayal› biyokimyasal ölçütlerin tüberküloz plörezi ile parapnömonik efüzyonun ayr›c› tan›-
s›nda faydal› olmad›¤›n› düflünmekteyiz.
Objectives: Tuberculous pleurisy and parapneumonic effusion
are common causes of pleural effusion in Turkey. The aim of
this study was to assess the biochemical characteristics in the
differential diagnosis of infectious effusions.
Material and Method: The biochemical characteristics of serum and pleural effusion samples of 26 patients with tuberculous pleurisy, 44 patients with parapneumonic pleurisy, and
62 patients with congestive heart failure who had underwent
thoracentesis in a university hospital were retrospectively
analyzed. Statistical analysis was done using SPSS 10.0 software.
Results: The mean ages of the patients were 37 for tuberculous pleurisy, 40 for parapneumonic effusion, and 64 for congestive heart failure. Weight loss was significantly frequent in
patients with tuberculous pleurisy when compared to other
groups. Total leukocyte count in the fluid was 556/mm3 for
transudates, 11424/mm3 for tuberculosis, and 8260/mm3 for
parapneumonic effusion. There was not a significant difference in pleural fluid LDH levels, ratio of pleural fluid LDH to
serum LDH, pleural fluid albumin and total protein levels,
and ratio of pleural fluid total protein to serum total protein
between tuberculous pleurisy and parapneumonic effusion.
Conclusions: We think that biochemical criteria based on the
pleural fluid or serum is not helpful in the differential diagnosis between tuberculous pleurisy and parapneumonic effusion.