The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model

Eren K., Turgut B., Akin M. M. , Demir T.

CURRENT EYE RESEARCH, vol.41, no.3, pp.367-376, 2016 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.3109/02713683.2015.1023460
  • Journal Name: CURRENT EYE RESEARCH
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.367-376
  • Keywords: Experimental, glaucoma, mitomycin-C, sirolimus, sunitinib, trabeculectomy, GROWTH-FACTOR-BETA, TYROSINE KINASE INHIBITOR, CHOROIDAL NEOVASCULARIZATION, SUBCONJUNCTIVAL, RAPAMYCIN, FIBROBLASTS, MTOR, PDGF, MODULATION, MECHANISM

Abstract

Purpose: To investigate the effects of sirolimus and sunitinib on wound healing in experimental glaucoma filtering surgery (GFS).