Panniculitis in Anti-MDA-5 Positive Juvenile Dermatomyositis: A Case Report

Ayduran S., Kilbas G., Tigrak S. N., YÜKSEL S., Comut E., Turkucar S.

Journal of the Nepal Medical Association, vol.63, no.281, pp.61-64, 2025 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 281
  • Publication Date: 2025
  • Doi Number: 10.31729/jnma.8874
  • Journal Name: Journal of the Nepal Medical Association
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, IBZ Online, CAB Abstracts, Directory of Open Access Journals
  • Page Numbers: pp.61-64
  • Keywords: anti MDA-5, dermatomyositis, panniculitis
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Panniculitis is a rare clinical finding in dermatomyositis. There are few reported cases in the medical literature. In this report, we describe a 17-year-old male patient with anti-MDA5 positive hypomyopathic dermatomyositis who, eight months after diagnosis, presented with indurated nodules on the right forearm and right thigh despite methotrexate and monthly intravenous immunoglobulin treatment. A skin biopsy revealed lobular panniculitis with lymphocytic infiltrate. His lesions were successfully controlled with hydroxychloroquine and azathioprine. This article presents a case regarding the rarity of panniculitis in juvenile dermatomyositis and its treatment strategy.