Linezolid alone and in combination with rifampicin prevents experimental vascular graft infection due to methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis


Sacar M. , Sacar S. , Kaleli I., Önem G., Turgut H., Gökşin I., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.139, sa.2, ss.170-175, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 139 Konu: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.jss.2006.10.003
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.170-175

Özet

Background. In this report we describe the in vivo antibacterial activity of linezolid in an experimental graft infection model in rats and compare it with teicoplanin. The objective of this study was also to determine the effects of the interaction of linezolid when it was combined with rifampicin and test this effect against strains of methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis.