Evaluation of circulating cell free DNA in plasma as a biomarker of different thyroid diseases

ÇAĞLAR Ö., Cilgin B., Eroglu M., ÇAYIR A.

BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol.86, no.3, pp.321-326, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 86 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.1016/j.bjorl.2018.12.008
  • Journal Name: BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.321-326
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Introduction: Many studies have been done on proteomics, genomics, epigenetic, immuno-genetics in many body fluids. Among these, circulating cell-free DNA (ccfDNA) entered the literature in 1948, but it has not been studied for many years due to technological deficiencies. Following recent advances, geno-metastasis has been mentioned and new research is needed in this area. ccfDNA is known to be an important biomolecule in this regard.