Multivoxel magnetic resonance spectroscopy in gliomatosis cerebri

Uysal E., Ertürk Ş. M. , Yıldırım H., KARATAĞ O. , Can M., Tanik C., ...Daha Fazla

ACTA RADIOLOGICA, cilt.46, sa.6, ss.621-624, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Konu: 6
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1080/02841850510021751
  • Sayfa Sayıları: ss.621-624


Gliomatosis cerebri is a rare entity with non-specific clinical and conventional magnetic resonance imaging (MRI) findings; accurate diagnosis is a differential diagnostic challenge. MR spectroscopy has recently been introduced as a useful diagnostic tool for detection of this entity. We present a gliomatosis cerebri case in which we made the radiological diagnosis using the MR spectroscopy findings; the diagnosis was confirmed by subsequent biopsy and histopathologic evaluation. Multivoxel spectroscopy (CSI, PRESS, 1500/135) shows a marked increase in Cho/NAA (6.6), normal to mild increase in Cho/Cr (1.2), and marked decrease in NAA/Cr (0.2) compared with the normally appearing contralateral side (Cho/NAA: 0.8, Cho/Cr: 0.9, NAA/Cr: 1.2).