MEFV gene mutation spectrum in familial Mediterranean fever (FMF)


COKER I., COLAK A., YOLCU I., Turkon H. , Nalbantoglu S. M.

ZEITSCHRIFT FUR RHEUMATOLOGIE, cilt.70, ss.511-515, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 70 Konu: 6
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1007/s00393-011-0751-4
  • Dergi Adı: ZEITSCHRIFT FUR RHEUMATOLOGIE
  • Sayfa Sayıları: ss.511-515

Özet

Familial Mediterranean fever (FMF), an autosomal recessive autoinflammatory disorder, is characterized by recurrent, self-limiting fever and serositis which is frequently seen in Mediterranean populations. In this study, we retrospectively evaluated the MEFV gene mutation distribution of 883 citizens of the Aegean region with preliminary diagnosis of FMF who were referred to the Tepecik Research and Education Hospital's Tissue Typing and Molecular Diagnostic Laboratory (Izmir, Turkey) between 2006 and 2009.