The efficacy of Ankaferd Blood Stopper (R) in an experimental Asherman syndrome model created in rats


Buyuk B. , BEYAZIT F.

TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.16, ss.7-14, 2019 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 16 Konu: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/tjod.galenos.2018.21298
  • Dergi Adı: TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY
  • Sayfa Sayıları: ss.7-14

Özet

Objective: Asherman syndrome (AS) is a progressive disease involving menstrual disorders, recurrent pregnancy losses, and infertility developing as a result of partial or full blockade of the uterine cavity with adhesions. AS generally develops after trauma to the basal layer of the endometrium. In spite of a variety of methods such as adhesiolysis, inserting intrauterine devices, and administering high doses of estrogen, treatments remain insufficient. This study aimed to assess the effects of local intrauterine Ankaferd Blood Stopper (ABS) administration in inducing endometrial proliferation and building a normal endometrial layer in a rat model.