Diagnosis of lung adenocarcinoma with clear cell features in pleural effusion: Cytomorphologic features, immunocytochemical studies, and differential diagnosis

Erdogan-Durmus S., Yulek Ö., Erdem Z.

Journal of Cytology, vol.39, no.3, pp.134-136, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.4103/joc.joc_48_22
  • Journal Name: Journal of Cytology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, Directory of Open Access Journals
  • Page Numbers: pp.134-136
  • Keywords: Clear cell morphology, lung adenocarcinoma, metastasis, serous effusions
  • Çanakkale Onsekiz Mart University Affiliated: No

Abstract

Clear cell adenocarcinoma (CCA) of the lungs is no longer referred to as a subtype in recent classifications of lung adenocarcinoma. Like signet ring features, clear cell features are regarded as cytological features rather than histological subtypes. Additionally, in serous fluids, adenocarcinoma metastasis with clear cell features is a diagnostic challenging entity due to other tumors that come to mind first during the differential diagnosis. Here we report a case, diagnosed as CCA of lung metastasis in pleural fluid and evaluated its differential diagnosis.