Synthesis, Molecular Structure, Biological Activity, and Sensor Properties of (E)-2-[(3,5-Bis(trifluoromethyl)phenylimino)methyl]-4,6-dichlorophenol

Zeyrek C., Boyacıoğlu B., Demir N., Tümer Y., Kiraz A., Ünver H., ...More

Russian Journal of General Chemistry, vol.91, no.2, pp.279-284, 2021 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 91 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1134/s107036322102016x
  • Journal Name: Russian Journal of General Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core
  • Page Numbers: pp.279-284
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

© 2021, Pleiades Publishing, Ltd.Abstract: In the present study, a Schiff base (E)-2-[(3,5-bis(trifluoromethyl)phenylimino)methyl]-4,6-dichlorophenolhas been synthesized. Its spectroscopic and X-ray single-crystal data have beencompared with the results of theoretical calculations based on the DFT method,as well as molecular electrostatic potential (MEP), HOMO and LUMO, and nonlinearoptical (NLO) effects. Antimicrobial activity of the compound has been testedagainst some bacteria and fungi. According to UV-Vis and agarose gelelectrophoresis methods, the compound interacts with DNA electrostatically andbreaks it oxidatively. Antioxidant activity of the compound measured by the DPPHmethod, is lower than that of BHT.