Synthesis, Molecular Structure, Biological Activity, and Sensor Properties of (E)-2-[(3,5-Bis(trifluoromethyl)phenylimino)methyl]-4,6-dichlorophenol


Zeyrek C., Boyacıoğlu B., Demir N. , Tümer Y., Kiraz A., Ünver H., ...More

Russian Journal of General Chemistry, vol.91, no.2, pp.279-284, 2021 (Journal Indexed in SCI Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 91 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.1134/s107036322102016x
  • Title of Journal : Russian Journal of General Chemistry
  • Page Numbers: pp.279-284

Abstract

© 2021, Pleiades Publishing, Ltd.Abstract: In the present study, a Schiff base (E)-2-[(3,5-bis(trifluoromethyl)phenylimino)methyl]-4,6-dichlorophenolhas been synthesized. Its spectroscopic and X-ray single-crystal data have beencompared with the results of theoretical calculations based on the DFT method,as well as molecular electrostatic potential (MEP), HOMO and LUMO, and nonlinearoptical (NLO) effects. Antimicrobial activity of the compound has been testedagainst some bacteria and fungi. According to UV-Vis and agarose gelelectrophoresis methods, the compound interacts with DNA electrostatically andbreaks it oxidatively. Antioxidant activity of the compound measured by the DPPHmethod, is lower than that of BHT.