Epicardial Adipose Tissue Thickness in Hemodialysis Patients


Altun B., Tasolar H., Eren N., Binnetoglu E., Altun M., Temiz A., ...More

ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, vol.31, no.8, pp.941-946, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 8
  • Publication Date: 2014
  • Doi Number: 10.1111/echo.12498
  • Journal Name: ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.941-946
  • Keywords: epicardial adipose tissue, hemodialysis, atherosclerosis, INTIMA-MEDIA THICKNESS, CHRONIC KIDNEY-DISEASE, CAROTID-ARTERY, CARDIOVASCULAR-DISEASE, CORONARY ATHEROSCLEROSIS, FAT THICKNESS, RISK, ECHOCARDIOGRAPHY, ASSOCIATION, MORTALITY
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Aim: Hemodialysis (HD) patients had higher cardiovascular mortality and it is related to atherosclerosis. Epicardial adipose tissue (EAT) thickness is a marker of atherosclerosis and independent predictor of coronary artery disease. The aim of our study was to evaluate the relationship between EAT and carotid intima-media thickness (CIMT) predictors of early atherosclerosis in HD patients. Methods: The study included 62 HD patients and 40 healthy controls. EAT thickness and CIMT were measured by echocardiography in all subjects. Results: Epicardial adipose tissue thickness and CIMT were higher (6.98 +/- 1.67 vs. 3.84 +/- 0.73 mm, P < 0.001, 0.94 +/- 0.17 vs. 0.63 +/- 0.11 mm, P < 0.001, respectively) in HD patients than in control subjects. EAT thickness were correlated with CIMT, HD duration, age, and calcium. In addition, HD duration, CIMT, and age were independent predictors of EAT thickness on HD patients in regression analysis. Conclusion: Epicardial adipose tissue thickness may be a useful indicator of early atherosclerosis in HD patients.