Investigation of the effects of different doses of sugammadex on kidney histopathology in rabbits with acute renal failure

Ozturk O., ERBAŞ M.

ANAESTHESIA PAIN & INTENSIVE CARE, vol.23, no.1, pp.43-46, 2019 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 1
  • Publication Date: 2019
  • Journal Name: ANAESTHESIA PAIN & INTENSIVE CARE
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.43-46
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Objective: In our study, we hypothesised that using high doses, ie. 16 mg / kg sugammadex during general anesthesia after acute renal failure in rabbits would lead to a deteriorated renal histopathology due to the accumulation of rocuroniumsugammadex complex in the tubules. We aimed to investigate the effect of different doses of sugammadex (4 or 16 mg) on experimental kidney histopathology in rabbits with acute renal failure.