Antibacterial Activity of Two Endemic Hypericum (H. kazdaghensis and H. havvae) Against Methicillin-Resistant Staphylococcus aureus

Dülger G., Dülger B., AKI C.

ASIAN JOURNAL OF CHEMISTRY, cilt.22, sa.9, ss.7083-7086, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 9
  • Basım Tarihi: 2010
  • Dergi Adı: ASIAN JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.7083-7086
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Aqueous and ethanolic extracts obtained from endemic Hypericum kazdaghensis Gemici et Leblebici and H. havvae A. Guner have been investigated for its ability to inhibit 35 hospital isolated of methicillin-resistant Staphylococcus aureus (MRSA). Both aqueous and ethanolic extracts of the plant were effective on MRSA. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of the ethanolic extract with the greatest antibacterial activity were those of H. kazdagensis MIC 0.2-0.4 mg/mL and MBC 0.4-1.6 mg/mL, respectively.