Antifungal activity of Lamium tenuiflorum against some medical yeast Candida and Cryptococcus species

Dulger B.

PHARMACEUTICAL BIOLOGY, vol.47, no.5, pp.467-470, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 5
  • Publication Date: 2009
  • Doi Number: 10.1080/13880200902824881
  • Journal Name: PHARMACEUTICAL BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.467-470
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

The ethanol extracts obtained from the leaves, rootstock, and the combined formulation of endemic Lamium tenuiflorum Fisch.& Mey (Lamiaceae) have been investigated for their antifungal activities against medical yeast Candida and Cryptococcus species by the visual broth macrodilution method. The MIC values ranged from 3.12 to 25 mg/mL. All the extracts exhibited a strong antifungal effect against the yeast cultures. The extracts exhibited greater antifungal effect against Candida species than Cryptococcus species. Our findings support the use of this plant in traditional medicine for fungal infections especially against candidiasis.