Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism in psoriasis cases with hypertension.
Annals of Saudi medicine, cilt.34, sa.4, ss.340-5, 2014 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.5144/0256-4947.2014.340
- Dergi Adı: Annals of Saudi medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.340-5
- Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet
Özet
BACKGROUND AND OBJECTIVES: Psoriasis is a common autoimmune-mediated chronic, inflammatory skin disease. Although, the molecular mechanism is not completely understood, psoriasis is caused by genetic and non-genetic parameters. The current study aimed (1) to define genotype and allele frequency of endothelial nitric oxide synthase (eNOS Glu298Asp) gene polymorphism in hypertensive and/or non-hypertensive psoriatic patients (2) to investigate the possible relationship between the eNOS Glu298Asp polymorphism and the risk of hypertension among psoriatic patients in the Turkish population.