Tamoxifen Treatment for Riedel’s Thyroiditis: A Case Report

KARAKILIÇ E., SAYGILI E. S., YILDIZ Ö., KUYUCU A.

Endocrinology Research and Practice, cilt.27, sa.4, ss.245-247, 2023 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 4
  • Basım Tarihi: 2023
  • Doi Numarası: 10.5152/erp.2023.22015
  • Dergi Adı: Endocrinology Research and Practice
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.245-247
  • Anahtar Kelimeler: hypothyroidism, immunoglobulin G4-related disease, Riedel’s thyroiditis, tamoxifen
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Riedel’s thyroiditis is a rare variant of thyroiditis, and treatment recommendations are based on case reports. This thyroiditis form is considered among immunoglobulin G4-related diseases. Intense fibrosis of the thyroid gland can cause compression of the surrounding tissues and hypothyroidism. Glucocorticoids are recommended as first-line therapy, and tamoxifen is second-line therapy. Other immunosuppressive agents have also been used in some resistant cases. Our case was presented with a palpable firm mass in the neck, shortness of breath, and hypothyroidism. The exact diagnosis of Riedel’s thyroiditis was made after a pathological examination of a true-cut biopsy. We present the successful management of this case with glucocorticoid and tamoxifen combination treatment.