The effects of E-cadherin and bcl-2 on prognosis in patients with breast cancer

Kavgaci H., YILDIZ B., FİDAN E., Reis A., ÖZDEMİR F., ÇOBANOĞLU Ü., ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.111, no.9, pp.493-497, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 111 Issue: 9
  • Publication Date: 2010
  • Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.493-497
  • Keywords: E-cadherin, Bcl-2, breast cancer, EXPRESSION, P53, CARCINOMA, HER-2/NEU, MARKERS, BAX
  • Çanakkale Onsekiz Mart University Affiliated: No

Abstract

Background: Breast cancer is the most common malignancy in women. Axillary lymph node involvement and tumor size are the most significant prognostic factors in breast cancer. However, more factors are needed for evaluating the prognosis and individualizing the treatment in these patients. Intracellular adhesion molecule E-cadherin, antiapopitotic protein bcl-2, and p53 might have predictive and prognostic properties in breast cancer.