Erythrocyte CD38 as a prognostic marker in cancer

Albeniz I., Coşkun Ö., Türker Şener L., Baş A., Oktar A., Nurten R.

ONCOLOGY LETTERS, vol.12, no.4, pp.409-414, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1080/10245330701383841
  • Journal Name: ONCOLOGY LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.409-414
  • Keywords: CD38, cancer, prognostic markers, CEA, CYCLIC ADP-RIBOSE, SERUM-LEVELS, NAD GLYCOHYDROLASE, COLORECTAL-CARCINOMA, TUMOR PROGRESSION, PROSTATE-CANCER, OVARIAN-CANCER, ANTIGEN CD38, INTERLEUKIN-6, PROTEIN
  • Çanakkale Onsekiz Mart University Affiliated: No

Abstract

Background: Surface antigen CD38 which is a multifunctional protein with enzymatic and receptorial properties is involved in many processes of cell proliferation and activation. It is widely expressed within the hematopoetic system, and its expression is stimulated by proinflammatory cytokines. CD38-associated enzymatic activities in erythrocytes from cancer patients were investigated in this context.