Plant growth regulators play a vital role in fruit growth and development. However, effects of compounds belonging to the group of brassinosteroids have not been fully investigated in sweet cherries. One relatively new and one commonly applied growth regulator, 22S, 23S-Homobrassinolide and GA(3), respectively, were tested on 'Summit' and 'Regina' sweet cherries to determine the effects on fruit quality and physiological disorders. The substances were applied with a handgun sprayer at full bloom and at the beginning of fruit development (shuck split) for a 2-year period. GA(3) was applied at the concentrations of 25, 50, 100 mgL(-1) and 22S, 23S-Homobrassinolide at 0.05, 0.1, 0.5 mgL(-1). A combined application of 100 mgL(-1) GA(3) + 0.1 mgL(-1) 22S, 23S-Homobrassinolide was also applied. Effects of GA(3) and 22S, 23S-Homobrassinolide on fruit weight and size were evident for the concentrations applied and between the seasons for both of the cultivars. Combination of the both growth regulators and 100 mgL(-1) GA(3) alone produced longer fruits compared to the control trees in 'Regina'. The 22S, 23S-Homobrassinolide applications increased the firmness of the flesh slightly, but not to a great degree, compared to the GA(3) applications alone. The brightness of the red color was better with GA(3) applications in 'Summit' and 'Regina'. Brassinosteroid caused the fruits to have comparably dull red color. Total soluble solid contents of the cultivars were influenced by the substances and the year of the application. Stem resistance to separation from the fruit was under the influence of both treatments and seasons. In general, 22S, 23S-Homobrassinolide provided better stem resistance than the GA(3) applications. There were no effects of the substances on the development of physiological disorders.