Ocular Involvement of Brucellosis: A Pooled Analysis Study

Evlice O., Alkan Çeviker S., Filik A., Ağın A.

OCULAR IMMUNOLOGY AND INFLAMMATION, vol.0, no.0, pp.1-10, 2023 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 0 Issue: 0
  • Publication Date: 2023
  • Doi Number: 10.1080/09273948.2022.2164727
  • Journal Name: OCULAR IMMUNOLOGY AND INFLAMMATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1-10
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Aim: Brucellosis may affect the eye to varying degrees. The aim of this study was to investigate the ocular involvement of brucellosis and highlight key points.

Material and methods: Published literature in English language on the ocular involvement of brucellosis within last 30 years was evaluated. The PubMed international database was screened using certain keywords.

Results: The study included 27 publications evaluating a total of 159 cases. The most common types of ocular involvement were uveitis (52.2%) and conjunctivitis (17.6%). Most cases had concomitant systemic brucellosis (27.7%), and the most commonly used diagnostic method was a serological test (92.4%). Of all the patients, 37.1% recovered with sequelae.

Conclusion: Brucellosis may cause a wide range of ophthalmic manifestations, and an overlooked or late diagnosis may also lead to the development of sequelae or loss of vision. A routine ophthalmologic examination should be performed in all patients with systemic brucellosis.

Keywords: Brucella; brucellosis; endophthalmitis; ocular involvement; pooled analysis; uveitis