The effect of dexmedetomidine on myocardial ischemia reperfusion injury in streptozotocin induced diabetic rats


ARSLAN M., Poyraz F., KİRAZ H. A. , ALKAN M., Kip G., Erdem O., ...More

ANAESTHESIA PAIN & INTENSIVE CARE, vol.19, no.4, pp.444-451, 2015 (Peer-Reviewed Journal) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2015
  • Journal Name: ANAESTHESIA PAIN & INTENSIVE CARE
  • Journal Indexes: Emerging Sources Citation Index, Scopus
  • Page Numbers: pp.444-451

Abstract

Objective: Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio-protective effects of dexmedetomidine in a diabetic rat model of myocardial I/R injury.