Evidence for an association between tumor necrosis factor-alpha levels and lithium response


Guloksuz S., Altinbas K., ÇETİN E., Kenis G., Gazioglu S. B. , DENİZ G., ...More

JOURNAL OF AFFECTIVE DISORDERS, vol.143, pp.148-152, 2012 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 143
  • Publication Date: 2012
  • Doi Number: 10.1016/j.jad.2012.04.044
  • Journal Name: JOURNAL OF AFFECTIVE DISORDERS
  • Journal Indexes: Science Citation Index Expanded, Social Sciences Citation Index, Scopus
  • Page Numbers: pp.148-152

Abstract

Background: The role of inflammation in bipolar disorder has recently emerged as a potential pathophysiological mechanism. Tumor necrosis factor-alpha (TNIF-alpha) modulation may represent a pathogenic molecular target and a biomarker for staging bipolar disorder. In this context, the possible association between lithium response and TNF-alpha level was examined.