Biochemical and pathologic factors affecting technetium-99m-methoxyisobutylisonitrile imaging results in patients with primary hyperparathyroidism


Ozderya A., Temizkan S., Gul A. E. , Ozugur S., Cetin K., Aydin K.

ANNALS OF NUCLEAR MEDICINE, vol.32, no.4, pp.250-255, 2018 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1007/s12149-018-1239-y
  • Journal Name: ANNALS OF NUCLEAR MEDICINE
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.250-255
  • Keywords: Tc-99m MIBI, Parathyroid adenoma, P-glycoprotein, Ki-67 ratio, P-GLYCOPROTEIN EXPRESSION, MINIMALLY INVASIVE PARATHYROIDECTOMY, NEGATIVE SESTAMIBI SCINTIGRAPHY, PREOPERATIVE LOCALIZATION, CELL CONTENT, SENSITIVITY, SURGERY, ADENOMA, CALCIUM, WASHOUT

Abstract

Technetium 99 m methoxyisobutylisonitrile (Tc-99m MIBI) scintigraphy represents the most commonly utilized imaging modality for the detection of the diseased gland in patients with primary hyperparathyroidism (PHPT). In this study, we aimed to identify potential biological factors with an impact on MIBI sensitivity.