Melamine-based poly(azomethine) hydrogels: Mechanical, biodegradability, drug loading and antibacterial properties


Kamacı M., Kaya İ.

EUROPEAN POLYMER JOURNAL, vol.108, pp.107-115, 2018 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 108
  • Publication Date: 2018
  • Doi Number: 10.1016/j.eurpolymj.2018.08.035
  • Journal Name: EUROPEAN POLYMER JOURNAL
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.107-115
  • Keywords: Melamine, Hydrogel, Drug-release, Biodegradability, 5-Fluoro uracil, SCHIFF-BASE, IN-VITRO, DELIVERY, CONDUCTIVITY, POLYMERS, CHITOSAN, GUM

Abstract

In the present paper, a new series of biodegradable poly(azomethine) gels were prepared to investigate the usability as biomaterials. The structures of the hydrogels were characterized by using FT-IR and SEM analyses. Contact angle measurements were also performed to investigate hydrophobicity of the hydrogels. Thermal behavior of melamine-based poly(azomethine)s and hydrogels was performed using TG-DTA and DSC techniques. Mechanical properties of poly(azomethine) hydrogels were investigated using a tensile testing method. Biodegradability, drug loading or release performance, protein absorption, water uptake and antibacterial properties were also studied due to investigate usability of melamine-based hydrogels as biomaterials.