Influence of high-dose methotrexate therapy on the primordial follicles of the mouse ovary


Gol M., Saygili U., KOYUNCUOĞLU ÜLGÜN M., Uslu T.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, cilt.35, ss.429-433, 2009 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 35 Konu: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1447-0756.2008.00945.x
  • Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Sayfa Sayıları: ss.429-433

Özet

Objective: High-dose methotrexate (MTX) is one of the most prescribed agents in many malignant diseases affecting girls and young women of reproductive ages. This animal study directly measures the primordial follicle loss following exposure to high-dose MTX.