Evaluation of the Process of Acute Treatment for Depression in Terms of Monitoring Activity and Sleep Efficiency with Actigraphy


Akıncı E. , İnce B.

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, vol.31, no.2, pp.213-218, 2021 (Journal Indexed in SCI Expanded)

  • Publication Type: Article / Article
  • Volume: 31 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.5152/pcp.2021.21335
  • Title of Journal : PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
  • Page Numbers: pp.213-218

Abstract

Background: This study aimed to evaluate and follow-up the process of acute treatment for depression in  terms  of  activity  and  sleep  efficiency using  actigraphy,  and  thus  increase  the  opportunities  for objective measurement in the monitoring of treatment.

Methods:  A  total  of  20  patients  with  depression,  and  22  and  age-  and  gender-matched  healthy volunteers  were  included  in  the  study. All  subjects  were  evaluated  using  a  sociodemographic  data form, the Hamilton Depression Rating Scale (HDRS), and actigraphy for measurement of motor activity and sleep efficiency.  

Results: The activity levels and sleep efficiency of the controls were significantly higher than the pre-and post-treatment activity levels and sleep efficiency of the patients. After the treatment process, both motor activity and sleep efficiency were found to be significantly increased in the patients. A  highly significant negative correlation was found between the  HDRS  scores and average activity counts for active intervals (r = −0.779, P < .001), and between the HDRS scores and sleep efficiency  (r = −0.616, P < .001). On the other hand, a significant negative effect was found between depression and average activity counts for active intervals (RR:0.880; 95% CI:0.782-0.991).

Conclusions: Actigraphy is a useful technique for quantifying physical activities and sleep efficiency in depressed patients. Furthermore, it may provide objective follow-up data in assessing the effects of treatment for depression.