The aim of this study, is to research an answer to the question of have mobile phones effects on periodontal tissues and teeth. Twenty eight Wistar Albino adult male rats (4 months) with initial average weight of 267 +/- 15 g were obtained from the Medical Science Application and Research Center, caged individually and fed with standard pelletted food (TAVAS Inc. Adana, TR). They were separated into three groups such as cage control (n = 7), sham exposed (n = 7) and experimental (n = 14) and kept on a 14/10 h light/dark schedule. The rats were confined in a Plexiglas carousel and rat heads in the carousel exposed to 900 MHz microwave exposure emitted from generator. For the study group, rats exposed to the radiation 2 h per day (7 days in a week) for 10 months. Although, there was no statistical difference determined among the groups of experimental and sham groups (p>0.05), there were numerically more individuals effected of RF radiation in the experimental group. In our study is the statistically significant difference among the groups of experimental, sham and control groups in the case of vasodilatation in periodontal ligament and alveolar bone (p<0.05). By the histopathologic evaluation abnormal changes like vasodilatation and focal bleeding areas were determined in periodontal ligament, alveolar bone, gingiva and pulpa among some individuals. These degenerations were in different levels. These findings of our study indicates that there is need to more animal, human being and epidemiologic studies including much more individuals.