Protective effect of decorin on acute ischaemia-reperfusion injury in the rat kidney
ARCHIVES OF MEDICAL SCIENCE, cilt.7, sa.2, ss.211-216, 2011 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 7 Sayı: 2
- Basım Tarihi: 2011
- Doi Numarası: 10.5114/aoms.2011.22069
- Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.211-216
- Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet
Özet
Introduction: Transforming growth factor-beta 1 (TGF-beta 1) has a crucial role in collagen synthesis and fibrosis. TGF-beta 1 can be antagonized and/or reduced by the action of certain agents. We propose to identify the role of decorin in treatment of tubular and interstitial fibrosis and in the inhibition of TGF-beta 1 in an acute ischaemic kidney.