Effect of different doses of 2aEuroaminoethoxydiphenyl borate on intestinal ischemia-reperfusion injury


Basbug M., Yildar M., Yaman I., Cavdar F., ÖZKAN Ö. F. , AKŞİT H., ...More

EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA, vol.49, no.1, pp.32-37, 2017 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.1007/s10353-016-0452-y
  • Journal Name: EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.32-37

Abstract

Background Acute mesenteric ischemia is a life-threatening clinical entity. 2-Aminoethoxydiphenyl borate (2-APB) is a membrane-permeable modulator of intracellular inositol triphosphate-induced calcium release. We investigated the effects of different 2-APB doses on intestinal ischemia-reperfusion injury in an experimental rat model.