Does anti-oxidant prophylaxis with melatonin prevent adverse outcomes related to increased oxidative stress caused by laparoscopy in experimental rat model?


CAY A., IMAMOGLU M., Unsal M. A. , AYDIN S., ALVER A., AKYOL A., ...More

JOURNAL OF SURGICAL RESEARCH, vol.135, no.1, pp.2-8, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 135 Issue: 1
  • Publication Date: 2006
  • Doi Number: 10.1016/j.jss.2005.12.025
  • Title of Journal : JOURNAL OF SURGICAL RESEARCH
  • Page Numbers: pp.2-8

Abstract

Background. We hypothesized that prophylaxis with an anti-oxidant should prevent potential adverse outcomes of laparoscopy related to increased oxidative stress in splanchnic organs, including small intestine, liver, and kidneys, and melatonin is the most appropriate agent for this purpose.