Unexpected severe hepatotoxicity of ciprofloxacine: two case reports

ALAN C., Kocoglu H., ERSAY A. R., Ertung Y., KURT H. A.

DRUG AND CHEMICAL TOXICOLOGY, cilt.34, sa.2, ss.189-191, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3109/01480545.2010.495392
  • Dergi Adı: DRUG AND CHEMICAL TOXICOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.189-191
  • Anahtar Kelimeler: Complication, ciprofloxacin, hepatotoxicity, URINARY-TRACT INFECTIONS, ACUTE LIVER-INJURY, EFFICACY, SAFETY, HEPATITIS
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Ciprofloxacin is a fluoroquinolone antibiotic that has a relatively low rate of occurence of adverse side effects. However, increasing evidences suggest that ciprofloxacin may cause unexpected severe liver damage. Especially, the risk of hepatotoxicity is significantly higher in elderly men receiving drug for a long time. In this article, 2 cases of unexpected severe hepatoxicity of ciprofloxacin are presented.