Frequencies of micronuclei (MNi), nucleoplasmic bridges (NPBs), and nuclear buds (NBUDs) in farmers exposed to pesticides in Çanakkale, Turkey

COŞKUN M.

Environment International Environ Int, vol.37, no.1, 2011 (SCI-Expanded)

  • Publication Type: Article / Article
  • Volume: 37 Issue: 1
  • Publication Date: 2011
  • Journal Name: Environment International Environ Int
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

This study aimed to determine the incidence of micronuclei (MNi), nucleoplasmic bridges (NPBs), and nuclear buds (NBUDs) in peripheral blood lymphocytes due to direct exposure to pesticides among 46 farmers in Çanakkale, Turkey. 48 non-exposed individuals living in the same socioeconomic conditions were chosen as control. In addition, a cytokinesis-block proliferation index (CBPI) was calculated. MNi and NBUDs frequencies were signi?cantly higher among the farmers (pb0.05). Although the NPB frequency of the farmers was higher than the controls, there was no statistical difference. Multiple linear regression analysis showed that apart from gender, no signi?cant effects of various confounding factors were observed. Regarding CBPI, data obtained for the controls were higher than that of the farmers; however, there was no statistically signi?cant difference.