EFFECTS OF CYP2C19 AND P2Y12 GENE POLYMORPHISMS ON CLINICAL RESULTS OF PATIENTS USING CLOPIDOGREL AFTER ACUTE ISCHEMIC CEREBROVASCULAR DISEASE


Sen H. M., SILAN F., SILAN C., Degirmenci Y., Kamaran O. H.

BALKAN JOURNAL OF MEDICAL GENETICS, cilt.17, sa.2, ss.37-41, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.2478/bjmg-2014-0072
  • Dergi Adı: BALKAN JOURNAL OF MEDICAL GENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.37-41
  • Anahtar Kelimeler: Ischemic cerebrovascular disease (ICVD), clopidogrel, CYP2C19 and P2Y12 gene polymorphisms, CORONARY-ARTERY-DISEASE, PLATELET REACTIVITY, EVENTS, INTERVENTION, POPULATION, GENOTYPE, THERAPY, STROKE, IMPACT, RISK
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

The CY2C19 and P2Y12 gene polymorphisms are responsible for resistance to clopidogrel, known as drug unresponsiveness. In this study we researched the effect of gene polymorphism on clinical results of patients who began clopidogrel therapy after acute ischemic cerebrovascular disease.