EFFECTS OF CYP2C19 AND P2Y12 GENE POLYMORPHISMS ON CLINICAL RESULTS OF PATIENTS USING CLOPIDOGREL AFTER ACUTE ISCHEMIC CEREBROVASCULAR DISEASE


Sen H. M. , SILAN F., SILAN C., Degirmenci Y., Kamaran O. H.

BALKAN JOURNAL OF MEDICAL GENETICS, vol.17, no.2, pp.37-41, 2014 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.2478/bjmg-2014-0072
  • Journal Name: BALKAN JOURNAL OF MEDICAL GENETICS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.37-41
  • Keywords: Ischemic cerebrovascular disease (ICVD), clopidogrel, CYP2C19 and P2Y12 gene polymorphisms, CORONARY-ARTERY-DISEASE, PLATELET REACTIVITY, EVENTS, INTERVENTION, POPULATION, GENOTYPE, THERAPY, STROKE, IMPACT, RISK

Abstract

The CY2C19 and P2Y12 gene polymorphisms are responsible for resistance to clopidogrel, known as drug unresponsiveness. In this study we researched the effect of gene polymorphism on clinical results of patients who began clopidogrel therapy after acute ischemic cerebrovascular disease.