In-vitro determination of inhibitory effects of probiotic strains on Clostridioides difficile

Yalçin G. T., Tosun M. N., Demirel Zorba N. N.

Anaerobe, vol.81, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 81
  • Publication Date: 2023
  • Doi Number: 10.1016/j.anaerobe.2023.102737
  • Journal Name: Anaerobe
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Keywords: Antimicrobial activity, Clostridioides difficile, In-vitro, Inhibition, Probiotics
  • Çanakkale Onsekiz Mart University Affiliated: Yes

Abstract

Commercial probiotic strains inhibited C. difficile, and other Clostridium cultures with zones 14.2–78.9 mm. The highest inhibition was observed with commercial culture on C. difficile ATCC 700057. Organic acids were the leading cause of inhibition. Probiotic cultures may be used as a support culture or through fermented foods for treatment.