Research Information System
cumhuriyet medical journal, vol.42, no.2, pp.179-184, 2020 (Peer-Reviewed Journal)
SUMMARY
Objective: The aim of this study was to determine the predictive value of
mean platelet volume (MPV), neutrophil-to-lymphocyte ratio(NLR) and
platelet-to-lymphocyte ratio(PLR) in patients with acute middle cerebral
artery (MCA)branch infarction.
Method: This examination was performed on the files of 50 patients
followed up at the Anesthesia and Reanimation ICU of Onsekiz Mart
University Hospital between April 2017 and September 2019 for acute
occlusion in the MCA branch, with no previous history of an ischemic
stroke. These patients were assessed with the National Institutes of Health
Stroke Scale (NIHSS) and the Modified Rankin Score (mRS). The ratios of
the neutrophil and platelet countsto the lymphocyte count (NLR and PLR
ratios) within the first hour of the stroke and MPV were compared to a
control group.
Results: The study included 50 patients with the acute ischemia of the MCA
branch, of which 28 (56%) were female. The control group consisted of 50
healthy people, and 24 (48%) of these were female. The mean NIHSS score
of the patients was 11.4 ± 2.6, and their mean mRS was 2.5 ± 1.5.
Conclusions: In our study with patients who had acute middle cerebral
artery infarction, we found that the NLR, PLR, and MPV levels within the
first hour of stroke were higher in the patient group in comparison to the
control group ona statistically significant level. However, multicenter
studies with larger subject groups are needed for the use of hematological
parameters as biomarkers in an ischemic stroke.
Keywords: Cerebral artery infarct, mean platelet volume, neutrophil,
lymphocyte