A Case Series of Lymphangioleiomyomatosis, a Rare Cystic Lung Disease

Sedef S., MUTLU P.

Respirology Case Reports, cilt.14, sa.3, 2026 (ESCI, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 3
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1002/rcr2.70535
  • Dergi Adı: Respirology Case Reports
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Anahtar Kelimeler: pneumothorax, pulmonary lymphangioleiomyomatosis, sirolimus, tuberous sclerosis
  • Çanakkale Onsekiz Mart Üniversitesi Adresli: Evet

Özet

Lymphangioleiomyomatosis (LAM) is a rare interstitial lung disease that predominantly affects women of childbearing age. In this case series, we presented five cases diagnosed with LAM in our clinic in the last 2 years. All cases were female, and their ages ranged from 40 to 54 years. The primary symptoms of LAM seen in the cases were exertional dyspnea and cough. Radiological examination revealed multiple bilateral thin-walled air cysts on high-resolution computed tomography (HRCT) in all cases. In three cases, the diagnosis of LAM was made histopathologically by wedge resection. Awareness of this rare disease's clinical and radiological features is critical for early diagnosis and timely initiation of treatment.