Soil salinity is one of the most important abiotic stress factors which directly limits plant yield in agricultural production areas around the World. Salt stress also determines plant diversity in agricultural production areas. Development and revealing of plant response against to salt stress depends on physiological changes of plants controlled by complex molecular mechanisms which subsequently lead to development of tolerance. Sometimes, such changes and differences appear to be unique to the type of plant, but some other times, such responses are more common and similar in all plants. In addition, although such complex mechanisms appear to be developed directly related to salt stress per se, they may also be the results of other abiotic stress, like drought, or even biotic stress related responses. Therefore, better understanding of salt tolerance at both plant and mechanism levels will make significant contribution to develop better salt tolerant new plant varieties. The aim of this review was to make contribution on understanding of plant response against to salt stress based on current literature.