Serum cortisol levels following acute experimental spinal cord injury


GEZİCİ A. R. , KARAKAŞ A., Ergun R., GÜNDÜZ B.

NEUROLOGIA I NEUROCHIRURGIA POLSKA, vol.43, no.4, pp.352-357, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 4
  • Publication Date: 2009
  • Title of Journal : NEUROLOGIA I NEUROCHIRURGIA POLSKA
  • Page Numbers: pp.352-357

Abstract

Background and purpose: Cortisol has neuroprotective effects. We monitored the serum cortisol levels after cervical and thoracic spinal cord injury (SCI) in four groups of rats. Materials and methods: Forty male Sprague-Dawley rats were randomized to four groups. The control group received neither laminectomy nor SCI. The sham group received laminectomy without SCT. The cervical spinal trauma group received a C5-C6 laminectomy and spinal trauma at this level. The thoracic spinal trauma group received a T6-T7 laminectomy and spinal trauma. Blood samples were drawn 2, 6, 12 and 24 hours after surgeries and assayed immediately.