The present study aimed to investigate the effect of somatic cell count (SCC) of raw cow's milk on the volatile organic compound (VOC) profiles of yoghurt. Test yoghurt samples were produced from three batches of cow's milk with low, medium and high SCC, respectively. The VOCs were determined by gas chromatography-mass spectrometry (GC-MS) analysis. A lower diacetyl and acetoin content and a higher content of 2-heptanone, and butanoic and hexanoic acids were established in the yoghurt samples from batches with high SCC of above 1 000 000 cells/cm(3). The increased SCC of cow's milk had a negative effect on the volatile organic compound profiles of yoghurt.